RushRush 1W Lab Results + Truxilline Breakthrough Recap : coke | Torhoo darknet markets

First, off just wanted to give RR a shout out, https://torhoo.cc/go.php?u=TDNVdlVuVnphRkoxYzJnPQ==# continues to deliver exactly what he promises—clean, potent, euphoric perico with zero edge. The 1W brick tested at 91% purity with no adulterants, which was no surprise given the source. It ran clean, energetic, and incredibly smooth, with that unmistakable signature balance plus that taste/smell we all love. Also everyone, please excuse the delay, I wanted to get this out about two weeks ago, but, Kykeon was down for a bit due to admin maintenance.

Funny Session Story

A few 50mg bumps into an awesome evening I was having with the Mrs. we were drinking some iced tea and I was getting ready for round 2 or 3 at that point, I started cracking up about the “1 Papi, 1 Mami… 2 Mamis… 3 Mamis…” review while chopping up about 400mg to put in a bullet, and to my horror I laughed a little too hard and accidentally antiqued my wife everywhere... (FFS). I knew what to do, and in between snorting and licking, my face was almost entirely numb. Luckily it didn’t kill me mojo, and I was able to continue—but she ended up having to lick my face because it was just everywhere. I guess there are worse things that could happen…

Now for the more technical update...

While reviewing some earlier Kykeon sample results—including Bolivian leaf samples 633 and 634 submitted for ethnobotanical profiling—I noticed something odd: no trace of truxillines. Given that Casale and Moore (1994) reported truxillines at a range of 2–13% in nearly all illicit cocaine samples and up to 61.2% in Colombian coca leaf (Table 4, J. Chromatogr. A), their complete absence in the results stood out.

This prompted a closer look at Kykeon’s MRM transitions. Their default detection method used a 659 → 581 transition at CE 20, which might have been missing low-abundance or matrix-suppressed signals. Based on work by Botelho (2011) and Carby-Robinson (2021), I suggested trying 659 → 182 or 659 → 131 at a higher collision energy (35–40 eV). These transitions showed stronger fragment response in prior literature and seemed promising for detecting the elusive dimeric alkaloids.

To Kykeon’s credit, they approached this feedback collaboratively and tweaked their method to include the alternate transitions. And sure enough—truxillines started appearing in refined samples.

This meant that many earlier tests may or may not have been under reporting total alkaloid content by failing to account for the truxilline fraction, which can be substantial, especially in Colombian-origin material.

Confirmation came soon after in new batches submitted by Mr. Zoidberg, which clearly showed truxilline presence under the updated parameters.

Now you may be asking—why is this relevant?? Well, there is a complete lack of pharmacological data regarding bioassay. We’ve all noticed that some regional coke is edgier than others—i.e., Colombians are speedier, Bolivians are in between Colombians and Peruvians, with the Peruvians being the most mellow, back-of-the-envelope.

In the same paper that helped me identify the MRM transition needed to detect truxillines, my boy https://torhoo.cc/go.php?u=TDNVdmIyNWtaWEozWldjeE1qTT0=# noticed and said, interestingly, Colombians have the highest truxilline concentrations out of every other coca plant—nearly 20x the amount.

This isn’t just a technical win—it opens up better profiling for ethnobotanical work, more accurate forensic fingerprinting, and deeper insight into regional differences between coca types. And that’s just the start.

Coca Leaf Truxillines Percentage Present
Isomeric Truxillines
Bolivia: 2.53%
Peru: 2.99%
Ecuador: 13.04%
Colombia: 61.20%

I can't conclusively say this accounts 100% for why Colombians are speedier than Peruvians, but I think it's a starting point of a discussion to delve further into understanding what we are putting in our bodies. Just like some people are either Indica or Sativa fans, I believe having this data now might start looking into why some Coca is edgier than others. When you think of the old mention of the Rolling Stones doing USP cocaine, the cocaine they were doing had no secondary alkaloids—it was just pure cocaine HCl, so that could be it. Also, there are 18 alkaloids total in various concentrations or presence within the 4 main tropane alkaloid producing subspecies of the coca plant, including some alkaloids like nicotine.

Breakdown of alkaloid content and methodology used:

1) Casale states that the max theoretical purity for an illicit sample is 98%
2) Casale also states that the typical moisture and trace solvents remaining is 2%
3) Using the "Normalization to Known Anchor Analyte" method — a semi-quantitative technique identify the remaining 7% of remaining alkaloids
3) I am using the 91% purity result as the "Anchor" substance as that is fully quantified
4) Now that we know in theory that there are only 3 other remaining identified alkaloids, we can use their area to distribute over the remaining 7% as seen below
5) Is this 100% accuracy no, but this is from what I remember the SOP for minor remaining within a fixed window when internal standards are unavailable or impractical for every compound. (SWGDRUG Semi-Quant Techniques)

Cocaine: 91.00% (known)
Truxillines: 1.847% (normalization to known anchor)
Cinnamoylcocaine: 4.716% (normalization to known anchor)
Norcocaine: 0.438% (normalization to known anchor)

Results: http://dumpliwoard5qsrrsroni7bdiishealhky4snigbzfmzcquwo3kml4id.onion/a/22c142